Barnard, Alun: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

Early doors ( Edo ) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking

Militi, Stefania, Maywood, Elizabeth S., Sandate, Colby R., Chesham, Johanna E., Barnard, Alun R., Parsons, Michael J., Vibert, Jennifer L., Joynson, Greg M., Partch, Carrie L., Hastings, Michael H.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.38 MB

english, 2016

2

When Clocks Go Bad: Neurobehavioural Consequences of Disrupted Circadian Timing

Barnard, Alun R., Nolan, Patrick M., Fisher, Elizabeth M. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 272 KB

english, 2008

3

Retinal Pigment Epithelium Defects Accelerate Photoreceptor Degeneration in Cell Type–Specific Knockout Mouse Models of Choroideremia

Tolmachova, Tanya, Wavre-Shapton, Silene T., Barnard, Alun R., MacLaren, Robert E., Futter, Clare E., Seabra, Miguel C.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2010

Language:

english

File:

PDF, 3.05 MB

english, 2010

4

Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

Chandler, Laurel, Yusuf, Imran, McClements, Michelle, Barnard, Alun, MacLaren, Robert, Xue, Kanmin

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.42 MB

2020

5

Characterization of a Dominant Cone Degeneration in a Green Fluorescent Protein–Reporter Mouse with Disruption of Loci Associated with Human Dominant Retinal Dystrophy

Lipinski, Daniel M., Yusuf, Mohammed, Barnard, Alun R., Damant, Christopher, Issa, Peter Charbel, Singh, Mandeep S., Lee, Edward, Davies, Wayne L., Volpi, Emanuela V., MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 1.24 MB

english, 2011

6

Dynamic in vivo quantification of rod photoreceptor degeneration using fluorescent reporter mouse models of retinitis pigmentosa

Orlans, Harry O., Barnard, Alun R., MacLaren, Robert E.

Journal:

Experimental Eye Research

Year:

2020

File:

PDF, 1.79 MB

2020

7

Assessment of AAV Dual Vector Safety in the Abca4 â/â Mouse Model of Stargardt Disease

McClements, Michelle E., Barnard, Alun R., Charbel Issa, Peter, MacLaren, Robert E.

Journal:

Translational Vision Science & Technology

Year:

2020

File:

PDF, 1.92 MB

2020

8

Optimization of In Vivo Confocal Autofluorescence Imaging of the Ocular Fundus in Mice and Its Application to Models of Human Retinal Degeneration

Charbel Issa, Peter, Singh, Mandeep S., Lipinski, Daniel M., Chong, Ngaihang V., Delori, François C., Barnard, Alun R., MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

9

Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice

Barnea-Cramer, Alona O., Wang, Wei, Lu, Shi-Jiang, Singh, Mandeep S., Luo, Chenmei, Huo, Hongguang, McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Lanza, Robert

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.52 MB

english, 2016

10

Codon-Optimized RPGR Improves Stability and Efficacy of AAV8 Gene Therapy in Two Mouse Models of X-Linked Retinitis Pigmentosa

Fischer, M. Dominik, McClements, Michelle E., Martinez-Fernandez de la Camara, Cristina, Bellingrath, Julia-Sophia, Dauletbekov, Daniyar, Ramsden, Simon C., Hickey, Doron G., Barnard, Alun R., MacLare

Journal:

Molecular Therapy

Year:

2017

Language:

english

File:

PDF, 2.50 MB

english, 2017

11

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy

De Silva, Samantha R., Barnard, Alun R., Hughes, Steven, Tam, Shu K. E., Martin, Chris, Singh, Mandeep S., Barnea-Cramer, Alona O., McClements, Michelle E., During, Matthew J., Peirson, Stuart N., Han

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.35 MB

english, 2017

12

Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis

Salvetti, Anna P., Patrício, Maria I., Barnard, Alun R., Orlans, Harry O., Hickey, Doron G., MacLaren, Robert E.

Journal:

Translational Vision Science & Technology

Year:

2017

Language:

english

File:

PDF, 976 KB

english, 2017

13

Choroideremia: molecular mechanisms and development of AAV gene therapy

Patrício, Maria I, Barnard, Alun R, Xue, Kanmin, MacLaren, Robert E

Journal:

Expert Opinion on Biological Therapy

Year:

2018

Language:

english

File:

PDF, 1.76 MB

english, 2018

14

Repair of Retinal Degeneration following ExÂ Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors

Barnea-Cramer, Alona O., Singh, Mandeep, Fischer, Dominik, De Silva, Samantha, McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E.

Journal:

Molecular Therapy

Year:

2020

File:

PDF, 2.79 MB

2020

15

Non-Image-Forming Light Driven Functions Are Preserved in a Mouse Model of Autosomal Dominant Optic Atrophy

Perganta, Georgia, Barnard, Alun R., Katti, Christiana, Vachtsevanos, Athanasios, Douglas, Ron H., MacLaren, Robert E., Votruba, Marcela, Sekaran, Sumathi, Fox, Michael A.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

16

Differential roles for cryptochromes in the mammalian retinal clock

Wong, Jovi C. Y., Smyllie, Nicola J., Banks, Gareth T., Pothecary, Carina A., Barnard, Alun R., Maywood, Elizabeth S., Jagannath, Aarti, Hughes, Steven, van der Horst, Gijsbertus T. J., MacLaren, Robe

Journal:

The FASEB Journal

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

17

Filtration of Short-Wavelength Light Provides Therapeutic Benefit in Retinitis Pigmentosa Caused by a Common Rhodopsin Mutation

Orlans, Harry O., Merrill, Jonathon, Barnard, Alun R., Charbel Issa, Peter, Peirson, Stuart N., MacLaren, Robert E.

Journal:

Investigative Opthalmology & Visual Science

Year:

2019

Language:

english

File:

PDF, 1.60 MB

english, 2019

18

Association of Messenger RNA Level With Phenotype in Patients With Choroideremia

Fry, Lewis E., Patrício, Maria I., Williams, Jonathan, Aylward, James W., Hewitt, Harriet, Clouston, Penny, Xue, Kanmin, Barnard, Alun R., MacLaren, Robert E.

Journal:

JAMA Ophthalmology

Year:

2019

File:

PDF, 1006 KB

2019

19

Assessment of Tropism and Effectiveness of New Primate-Derived Hybrid Recombinant AAV Serotypes in the Mouse and Primate Retina

Charbel Issa, Peter, De Silva, Samantha R., Lipinski, Daniel M., Singh, Mandeep S., Mouravlev, Alexandre, You, Qisheng, Barnard, Alun R., Hankins, Mark W., During, Matthew J., MacLaren, Robert E., Hol

Journal:

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

20

The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification

Cross, Sally H., Mckie, Lisa, Hurd, Toby W., Riley, Sam, Wills, Jimi, Barnard, Alun R., Young, Fiona, MacLaren, Robert E., Jackson, Ian J., Barsh, Gregory S.

Journal:

Year:

2020

File:

PDF, 28.84 MB

2020

21

A clinical-grade gene therapy vector for pharmacoresistant epilepsy successfully overexpresses NPY in a human neuronal cell line

Patrício, Maria I., Barnard, Alun R., Green, Alexander L., During, Matthew J., Sen, Arjune, MacLaren, Robert E.

Journal:

Year:

2017

Language:

english

File:

PDF, 130 KB

english, 2017

22

Fundus Autofluorescence in the Abca4 −/− Mouse Model of Stargardt Disease—Correlation With Accumulation of A2E, Retinal Function, and Histology

Charbel Issa, Peter, Barnard, Alun R., Singh, Mandeep S., Carter, Emma, Jiang, Zhichun, Radu, Roxana A., Schraermeyer, Ulrich, MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 895 KB

english, 2013

23

A Semiautomated, Phenotypic, In Vitro Scratch Assay for Assessing Retinal Pigment Epithelial Cell Wound Healing

Storm, Tina, Wilson, Iain, Campbell, Ross, Bolinches-AmorÃ³s, Arantxa, Russell, Angela J., Davies, Stephen G., Barnard, Alun R., MacLaren, Robert E.

Journal:

Journal of Ocular Pharmacology and Therapeutics

Year:

2020

Language:

english

File:

PDF, 1.40 MB

english, 2020

24

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo

Tanya Tolmachova, Oleg E. Tolmachov, Alun R. Barnard…

Journal:

Journal of Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 890 KB

english, 2013

25

Visual Acuity after Retinal Gene Therapy for Choroideremia

Edwards, Thomas L., Jolly, Jasleen K., Groppe, Markus, Barnard, Alun R., Cottriall, Charles L., Tolmachova, Tanya, Black, Graeme C., Webster, Andrew R., Lotery, Andrew J., Holder, Graham E., Xue, Kanm

Journal:

New England Journal of Medicine

Year:

2016

Language:

english

File:

PDF, 288 KB

english, 2016

26

The electroretinogram as a method for studying circadian rhythms in the mammalian retina

Morven A. Cameron, Alun R. Barnard, Robert J. Lucas

Journal:

Journal of Genetics

Year:

2008

Language:

english

File:

PDF, 288 KB

english, 2008

27

Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial

MacLaren, Robert E, Groppe, Markus, Barnard, Alun R, Cottriall, Charles L, Tolmachova, Tanya, Seymour, Len, Clark, K Reed, During, Matthew J, Cremers, Frans P M, Black, Graeme C M, Lotery, Andrew J, D

Journal:

Year:

2014

Language:

english

File:

PDF, 5.94 MB

english, 2014

28

Cone Photoreceptor Neuroprotection Conferred by CNTF in a Novel In Vivo Model of Battlefield Retinal Laser Injury

Aslam, Sher A., Davies, Wayne I. L., Singh, Mandeep S., Charbel Issa, Peter, Barnard, Alun R., Scott, Robert A. H., MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2013

Language:

english

File:

PDF, 834 KB

english, 2013

29

Melanopsin Regulates Visual Processing in the Mouse Retina

Alun R. Barnard, Samer Hattar, Mark W. Hankins, Robert J. Lucas

Journal:

Current Biology

Year:

2006

Language:

english

File:

PDF, 266 KB

english, 2006

30

Association of Messenger RNA Level With Phenotype in Patients With Choroideremia

Fry, Lewis E., Patrício, Maria I., Williams, Jonathan, Aylward, James W., Hewitt, Harriet, Clouston, Penny, Xue, Kanmin, Barnard, Alun R., MacLaren, Robert E.

Journal:

JAMA Ophthalmology

Year:

2019

Language:

english

File:

PDF, 1006 KB

english, 2019

31

Effect of AAV-mediated rhodopsin gene augmentation on retinal degeneration caused by the dominant P23H rhodopsin mutation in a knock-in murine model

Orlans, Harry, Barnard, Alun R, Patricio, Maria Moreira, McClements, Michelle E, MacLaren, Robert E

Journal:

Human Gene Therapy

Year:

2020

File:

PDF, 1.64 MB

2020

32

RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain

Bridges, Esther, Sheldon, Helen, Kleibeuker, Esther, Ramberger, Evelyn, Zois, Christos, Barnard, Alun, Harjes, Ulrike, Li, Ji-Liang, Masiero, Massimo, MacLaren, Robert, Harris, Adrian

Journal:

Year:

2020

File:

PDF, 3.56 MB

2020

33

Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy

Hassall, Mark M., McClements, Michelle E., Barnard, Alun R., Patricio, Maria Ã., Aslam, Sher A., Maclaren, Robert E.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 3.31 MB

2020

34

Molecular Therapies for Choroideremia

Cehajic Kapetanovic, Jasmina, Barnard, Alun R., MacLaren, Robert E.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.97 MB

english, 2019

35

Melanopsin cells are the principal conduits for rod–cone input to non-image-forming vision

Güler, Ali D., Ecker, Jennifer L., Lall, Gurprit S., Haq, Shafiqul, Altimus, Cara M., Liao, Hsi-Wen, Barnard, Alun R., Cahill, Hugh, Badea, Tudor C., Zhao, Haiqing

Journal:

Year:

2008

Language:

english

File:

PDF, 1.22 MB

english, 2008

36

Specific deficits in visual electrophysiology in a mouse model of dominant optic atrophy

Alun R. Barnard, Peter Charbel Issa, Georgia Perganta, Pete A. Williams, Vanessa J. Davies, Sumathi Sekaran, Marcela Votruba, Robert E. MacLaren

Journal:

Experimental Eye Research

Year:

2011

Language:

english

File:

PDF, 835 KB

english, 2011

37

Vesicular Stomatitis Virus Glycoprotein– and Venezuelan Equine Encephalitis Virus-Derived Glycoprotein–Pseudotyped Lentivirus Vectors Differentially Transduce Corneal Endothelium, Trabecular Meshwork, and Human Photoreceptors

Lipinski, Daniel M., Barnard, Alun R., Issa, Peter Charbel, Singh, Mandeep S., De Silva, Samantha R., Trabalza, Antonio, Eleftheriadou, Ioanna, Ellison, Stuart M., Mazarakis, Nicholas D., MacLaren, Ro

Journal:

Human Gene Therapy

Year:

2014

Language:

english

File:

PDF, 1.66 MB

english, 2014

38

CNTF Gene Therapy Confers Lifelong Neuroprotection in a Mouse Model of Human Retinitis Pigmentosa

Lipinski, Daniel M, Barnard, Alun R, Singh, Mandeep S, Martin, Chris, Lee, Edward J, Davies, Wayne I L, MacLaren, Robert E

Journal:

Molecular Therapy

Year:

2015

Language:

english

File:

PDF, 1.34 MB

english, 2015

39

Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization

Charbel Issa, Peter, Barnard, Alun R., Herrmann, Philipp, Washington, Ilyas, MacLaren, Robert E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

40

Transplanted photoreceptor precursors transfer proteins to host photoreceptors by a mechanism of cytoplasmic fusion

Singh, Mandeep S., Balmer, Jasmin, Barnard, Alun R., Aslam, Sher A., Moralli, Daniela, Green, Catherine M., Barnea-Cramer, Alona, Duncan, Isabel, MacLaren, Robert E.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.30 MB

english, 2016

41

The Biological Activity of AAV Vectors for Choroideremia Gene Therapy Can Be Measured by In Vitro Prenylation of RAB6A

Patrício, Maria I., Barnard, Alun R., Cox, Christopher I., Blue, Clare, MacLaren, Robert E.

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

42

Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia

Xue, Kanmin, Jolly, Jasleen K, Barnard, Alun R., Rudenko, Anna, Salvetti, Anna P., Patrício, Maria I., Edwards, Thomas L., Groppe, Markus, Orlans, Harry O., Tolmachova, Tanya, Black, Graeme C., Webste

Journal:

Nature Medicine

Year:

2018

Language:

english

File:

PDF, 1.53 MB

english, 2018

43

Optimization of In Vivo Confocal Autofluorescence Imaging of the Ocular Fundus in Mice and Its Application to Models of Human Retinal Degeneration

Charbel Issa, Peter, Singh, Mandeep S., Lipinski, Daniel M., Chong, Ngaihang V., Delori, François C., Barnard, Alun R., MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2012

File:

PDF, 2.31 MB

2012

44

AAV-Mediated Gene Transfer of Human X-Linked Inhibitor of Apoptosis Protects against Oxidative Cell Death in Human RPE Cells

Shan, Haidong, Ji, Dan, Barnard, Alun R., Lipinski, Daniel M., You, Qisheng, Lee, Edward J., Kamalden, Tengku Ain, Sun, Xinghuai, MacLaren, Robert E.

Journal:

Investigative Ophthalmology & Visual Science

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

45

Residual photosensitivity in mice lacking both rod opsin and cone photoreceptor cyclic nucleotide gated channel 3 [alpha] subunit

BARNARD, ALUN R., APPLEFORD, JOANNE M., SEKARAN, SUMATHI, CHINTHAPALLI, KRISHNA, JENKINS, AARON, SEELIGER, MATHEAS, BIEL, MARTIN, HUMPHRIES, PETER, DOUGLAS, RON H., WENZEL, ANDREAS, FOSTER, RUSSELL G.

Journal:

Visual Neuroscience

Year:

2004

Language:

english

File:

PDF, 280 KB

english, 2004

46

An AAV dual vector strategy ameliorates the Stargardt phenotype in adult Abca4-/- mice

McClements, Michelle E, Barnard, Alun R, Singh, Mandeep S, Charbel Issa, Peter, Jiang, Zhichun, Radu, Roxana A, MacLaren, Robert E

Journal:

Human Gene Therapy

Year:

2018

Language:

english

File:

PDF, 2.06 MB

english, 2018

47

Molecular Therapies for Choroideremia

Cehajic Kapetanovic, Jasmina, Barnard, Alun R., MacLaren, Robert E.

Journal:

Year:

2019

File:

PDF, 2.97 MB

2019

48

Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues

Chandler, Laurel C., Barnard, Alun R., Caddy, Sarah L., Patrício, Maria I., McClements, Michelle E., Fu, Howell, Rada, Cristina, MacLaren, Robert E., Xue, Kanmin

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2019

Language:

english

File:

PDF, 2.35 MB

english, 2019

49

Novel gene function revealed by mouse mutagenesis screens for models of age-related disease

Potter, Paul K., Bowl, Michael R., Jeyarajan, Prashanthini, Wisby, Laura, Blease, Andrew, Goldsworthy, Michelle E., Simon, Michelle M., Greenaway, Simon, Michel, Vincent, Barnard, Alun, Aguilar, Carlo

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.29 MB

english, 2016

50

Mouse Slc9a8 Mutants Exhibit Retinal Defects Due to Retinal Pigmented Epithelium Dysfunction

Jadeja, Shalini, Barnard, Alun R., McKie, Lisa, Cross, Sally H., White, Jacqueline K., Robertson, Morag, Budd, Peter S., MacLaren, Robert E., Jackson, Ian J.

Journal:

Investigative Opthalmology & Visual Science

Year:

2015

Language:

english

File:

PDF, 1.73 MB

english, 2015

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски